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The Analytical Landscape in mRNA Therapeutics: Characterisation and Batch Release Strategies

Messenger-RNA (mRNA) drug therapeutics have recently emerged as promising and increasingly viable treatment modalities for cancer, cardiovascular diseases, rare gene...
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Overlap and Differences Between Bacterial Endotoxin Testing and Extractables and Leachables Testing

In the world of pharmaceutical and medical device manufacturing, there are various quality control tests that may be required for distinct product types from separat...
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The Next Generation of Pharmacological Treatments for Chronic Disease

The success of GLP-1 receptor agonists as obesity therapeutics has initiated a seismic shift in the treatment paradigm and conceptual understanding of non-communicab...
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Optimising Clinical Trials Through Integrated Biomarker and Translational Data Models

Clinical trials bridge the gap between discovery and patient care, but high failure rates, unpredictable patient responses and data variability continue to challenge...
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Overcoming the Challenges of Developing Cell and Gene Therapies for Autoimmune Disorders

Autoimmune diseases such as lupus, type 1 diabetes, inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and rheumatoid arthritis are complex condition...
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Peptide Libraries: Expanding Frontiers in Drug Discovery and Development

Peptide libraries have emerged as a transformative technology in drug discovery and development. These diverse collections of peptides, now mainly synthetic but also...
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Innovative Solutions for Future Cell Culture Development

The world is still confronting complex and urgent challenges. Populations continue to grow, while many societies are ageing, placing heavy burdens of chronic and deg...
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Powering the Future of Cell Therapy: Building Scalable Cell Therapy Manufacturing Across the UK

Chimeric antigen receptor (CAR) T-cell therapy is one of the most transformative breakthroughs in modern medicine. The concept of reprogramming a patient’s own immun...
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Is the PROTAC Party Just Getting Started?

A little over five years ago, the biotech world became intrigued with the promise of Antibody–Drug Conjugates (ADCs). Investors poured resources into CDMOs and produ...
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